Crystalline nephropathy acyclovir
WebAug 1, 2024 · Antivirals, including aciclovir, indinavir and ganciclovir, are the antimicrobial agents most often associated with crystal nephropathy, ... Acyclovir nephrotoxicity: a case report highlighting the importance of prevention, detection, and treatment of acyclovir-induced nephropathy. Case Rep Med. 2010; 2010: 602783. Google Scholar. WebMar 29, 2005 · Several different drugs have been described to induce crystal nephropathy, including acyclovir and the protease inhibitor indinavir. Renal injury associated with antiviral drugs involves diverse …
Crystalline nephropathy acyclovir
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WebTI - Acyclovir nephrotoxicity: a case report highlighting the importance of prevention, detection, and treatment of acyclovir-induced nephropathy. LID - 602783 [pii] LID - 10.1155/2010/602783 [doi] AB - Acute kidney injury is an unfortunate complication of acyclovir therapy secondary to crystal-induced nephropathy. WebThe patient's empiric treatment has been narrowed to acyclovir. (Herpes simplex encephalitis) Introduction Mechanism of action acyclovir is phosphorylated by a virally-encoded thymidine kinase acyclovir triphosphate acts as a guanosine analog, which impairs viral DNA polymerase, impairing viral DNA synthesis
WebAug 31, 2010 · Acute kidney injury is an unfortunate complication of acyclovir therapy secondary to crystal-induced nephropathy. It is characterized by a decrease in renal … WebNov 20, 2024 · Although the overall incidence of AKI has decreased and stabilized since the advent of ART, it remains a common finding in patients with HIV infection., HIV-dependent risk factors for AKI include a viral load of >10,000 copies/mL, a CD4 count of <200 cells/μL, a history of ART exposure, and an acquired immunodeficiency syndrome–defining illness.
WebThey describe aciclovir therapy as essentially safe, highlighting the potential risk of crystal nephropathy. This potentially life-threatening complication is well recognised in nephrology, but not ... High serum concentrations of the acyclovir main metabolite 9-carboxymethoxymethylguanine in renal failure patients with acyclovir-related ... WebAcyclovir therapy is associated with few adverse effects. The most common complaints associated with acyclovir therapy include nausea, diarrhea, and headache. Rapid infusions of intravenous acyclovir can result in reversible crystalline nephropathy.
WebAcyclovir decreases the symptoms of oral and genital herpes, but does not eliminate the virus. Topical acyclovir is indicated for initial genital herpes simplex virus. ... Nephrotoxicity (Crystalline Nephropathy) Kidney with Toxic-green-glow. Acyclovir may affect the renal tubules and cause increased BUN and creatinine levels indicating ... how to say can we watch a movie in spanishWebAcyclovir is an antiviral agent that works by interfering ... urine sediment examination for sulfa-drug-related crystals and casts is recommended to detect crystalline … north galisteo nmWebdevelopment of renal failure. Several different drugs have been described to induce crystal nephropathy, including acyclovir and the protease inhibitor indinavir. Renal injury associated with antiviral drugs involves diverse processes having effects on the renal transporters, as well as on tubule cells. In this article, we review the how to say can we get food in spanishWebJul 1, 2012 · Acyclovir is a widely used antiviral drug that can cause crystalluria and crystal nephropathy, particularly when administered through rapid intravenous infusion or in … how to say can we start in spanishWebMar 29, 2005 · Crystal nephropathy often develops within 24 to 48 hours of acyclovir administration. Three large series observed a 12% to 48% incidence of acyclovir-associated renal failure. In 38% to 50% of those … north galloway avenueWebMay 1, 2024 · Aciclovir is a guanosine derivative, highly speci c for herpes simplex (HSV) and varicella zoster (VZV) viruses. 2 The drug is activated inside infected cells … north gallia high school vinton ohioWebJan 1, 2016 · Crystal-induced nephropathy was suspected with acyclovir and the drug was withheld with concomitant initiation of aggressive intravenous fluids. The patient was administered Inj. furosemide 40 mg to prevent further crystal precipitation and induce the flushing out of occluding crystals. how to say canyon de chelly