High-quality genomes
WebJan 12, 2024 · In the vast majority of cases, short-read sequencing results in highly fragmented medium-quality MAGs, which are genome bins estimated to be more than 50% complete with less than 10%... WebFeb 7, 2024 · Abstract. Fission yeasts are an ancient group of fungal species that diverged from each other from tens to hundreds of million years ago. Among them is the preeminent model organism Schizosaccharomyces pombe, which has significantly contributed to our understandings of molecular mechanisms underlying fundamental cellular processes.The …
High-quality genomes
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WebJan 17, 2024 · Abstract. Outbred laboratory mice (Mus musculus) are readily available and have high fecundity, making them a popular choice in biomedical research, especially toxicological and pharmacological applications.Direct high throughput genome sequencing (HTS) of these widely used research animals is an important genetic quality control … WebApr 12, 2024 · High-quality chromosome-scale haplotype sequences of diploid genomes, polyploid genomes, and metagenomes provide important insights into genetic variation associated with disease and biodiversity. However, whole-genome short read sequencing does not yield haplotype information spanning whole chromosomes directly. …
WebApr 5, 2024 · Combining data from the Hi-C, Nanopore, and Illumina platforms to guide genome sequence assemblies has proven to be an effective method to improve assembly quality. Recently, several high-quality assemblies of reference genomes were generated through the integration of long reads and Hi-C data [21, 22, 69]. The long reads lead to low ... WebPAV-based genome-wide association study (PAV-GWAS) directly identified causal structural variations for silique length, seed weight and flowering time in a nested association …
WebOct 13, 2024 · The reconstruction of genomes is a critical step in genome-resolved metagenomics and for multi-omic data integration from microbial communities. Here, we … WebReference genomes are essential for metagenomic analyses and functional characterization of the human gut microbiota. We present the Culturable Genome Reference (CGR), a collection of 1,520 nonredundant, high-quality draft genomes generated from >6,000 bacteria cultivated from fecal samples of healthy humans.
WebJan 18, 2024 · A high-quality annotation is necessary to identify locations of coexpressed genes, the proximity of a variant to candidate genes, or regions associated with chromatin …
WebThe Integrated Microbial Genomes and Microbiomes (IMG/M) system serves as a community resource for comparative analysis and annotation of all publicly available genomes from three domains of life, in a uniquely integrated context. IMG/M provides tools for analyzing the functional capability of microbial communities based on their … shane warren dupontWebMar 27, 2024 · Comparison of genomic data from a museum specimen of a type D killer whale that stranded in New Zealand in 1955, with 3 modern genomes from the Cape Horn area, reveals high covariance and identity-by-state of alleles, suggesting these genomic characteristics and demographic history are shared among geographically dispersed … shane warne wife remarriedWebThe innovative Proximo algorithm uses the Hi-C data and scaffolding optimization to orient and sort WGS reads, producing very long contigs and high-quality, chromosome-scale scaffolds. Hi-C data and Proximo may also be integrated with other computational approaches (e.g. FALCON-Phase ), to enable 1 the production of “gold” and “platinum ... shane warren facebookWebFurther analysis of the high-quality genomes shed lights on the genomic basis of involutional reproduction, allomones biosynthesis and adaptive evolution in Chinese pepper, revealing a high consistent relationship between genomic evolution, environmental factors and phenotypic innovation. shane waroquierWebExplore your DNA with one of our high-definition sequencing products: Whole Genome Sequencing and Analysis. Our Whole Genome Sequencing and Analysis offers the most … shane warren jackson tnWebHigh-throughput technology makes sequencing to assemble new genomes accessible to everyone. Sequence polymorphisms are typically discovered by comparing resequenced … shane warren booksWebJan 5, 2024 · Comparative genomics is a science that compares genomic data either within a species or across species to answer questions in biomedicine. Laboratory experiments can then investigate the functional impact of those genomics similarities and differences. The history of comparative genomics goes back to the mid-1990s, but comparative … shane washington