Multidrug resistance-associated protein 4
Web6 iun. 2013 · MDR-associated protein 1 (MRP1) is another member of ABC transporters, which transports anticancer drugs across cellular membranes and reduces drug accumulation in the cells. MRP1 is closely... WebMultidrug resistance protein (MRP) 4 is a member of the MRP/ABCC subfamily of ATP-binding cassette transporters, which are capable of pumping a wide variety of …
Multidrug resistance-associated protein 4
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Web19 nov. 2024 · Multidrug Resistant Gram-Negative Bacteria in Community-Acquired Pneumonia Catia Cillóniz1,2,3,4, Cristina Dominedò5 and Antoni Torres1,2,3,4* Abstract This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2024. Other selected articles can be found online at … WebMultidrug resistance-associated protein 2 (MRP2) also called canalicular multispecific organic anion transporter 1 (cMOAT) or ATP-binding cassette sub-family C member 2 …
WebFurthermore, MRPs are also responsible for the ATP-driven efflux of physiologically important organic anions such as leukotriene C 4, folic acid, bile acids and cAMP. Thus, … Web4 apr. 2006 · There are now nine members of the multidrug resistance-associated protein family and eight of these (MRP1–8) are known to be organic anion transporters. …
WebFrom the structural point of view, only the bovine ortholog of the multidrug-resistance associated protein 1 (bMRP1) has been resolved. We here used ms-scaled molecular … WebMultidrug resistance-associated protein 6: Synonyms: ATP-binding cassette sub-family C member 6; Anthracycline resistance-associated protein; ... Baas F, Borst P: Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells. Cancer Res. 1999 Jan 1;59(1):175-82. [PubMed:9892204 ]
WebAcum 6 ore · The limited diversity in targets of available antibiotic therapies has put tremendous pressure on the treatment of bacterial pathogens, where numerous resistance mechanisms that counteract their ...
Web18 nov. 2014 · The multidrug resistance protein 4 (MRP4) belongs to the ATP-binding cassette transporter superfamily. 6 MRP4 is primarily involved in the efflux of nucleoside derivatives and has a role in... how to download imvu classic on windowsWebMultidrug resistance-associated protein 4 (MRP4) is a membrane transporter that mediates the cellular efflux of a wide range of anionic drugs and endogenous molecules. MRP4 transport can influence the pharmacokinetics of drugs and their metabolites, therefore more knowledge about the molecular determinants important for its transport function ... how to download imvu on hpWeb5 aug. 2024 · Multidrug resistance protein 4 (MRP4) or ATP-binding cassette subfamily C member 4 (ABCC4) is a multi-transmembrane protein that is able to transport a range of organic anionic compounds (both endogenous and xenobiotic) out of the cell. ... Borst, P., de Wolf, C., van de Wetering, K. Multidrug Resistance-Associated Proteins 3, 4, and 5. how to download imvu on chrome osWeb23 ian. 2014 · Therefore, the aim of this study was to conduct an expression analysis of four multidrug resistance-associated proteins (MRP1, 2, 4 and 5) in various in vitro and ex … how to download imvu on laptopWebMultidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation The second messengers cAMP and cGMP … leatherby\u0027s folsomWebMultidrug resistance-associated protein 4 (MRP4) controls ganciclovir intracellular accumulation and contributes to ganciclovir-induced neutropenia in renal transplant … leatherby\u0027s cafe rouge costa mesaWebMRP4 (multidrug resistance-associated protein 4; ABCC4 ), which exists at the apical membrane of renal proximal tubules, was reported to perform ATP-dependent urate anion excretion ( Km 1.5 mmol/L). 39 MRP4 is proposed to function as another exit pathway for … leatherby\u0027s elk grove