Spinphox
WebJan 1, 1999 · SpinPhox/iridium(I)-catalyzed asymmetric hydrogenation of cyclic α-alkylidene carbonyl compounds. Angewandte Chemie - International Edition 2014 Journal article DOI: 10.1002/anie.201309521 EID: 2-s2.0-84893619843. Contributors ... WebAlfa Chemistry offers 1,5-cyclooctadiene{(4S)-(-)-2-[(5R)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-phenyloxazole}iridium(I) tetrakis[3,5-bis ...
Spinphox
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WebThe utility of SpinPHOX ligand was exemplified by the reduction of α,α-bisbenzylidene derivatives to furnish spiro-acetal compounds in high enantioselectivity (Scheme 11). Substituents on the phenol ring did not influence the reaction. Iridium (III) species generated by the reduction of the iridium complex played a role as a WebSpinPhox/Ir-I catalysts have been demonstrated to be highly enantioselective in the asymmetric hydrogenation of the CC bonds in the exocyclic,-unsaturated cyclic carbonyls, …
WebTake it for a spin: SpinPhox/Ir I complexes are highly efficient and versatile in the enantioselective hydrogenation of a broad spectrum of exocyclic α,β-unsaturated … WebFeb 10, 2014 · An Ir/SpinPHOX complex catalyzed double asymmetric hydrogenation of 3,6-dialkylidene-1,4-dimethylpiperazine-2,5-dione has been developed, providing an efficient …
WebAug 20, 2024 · The first asymmetric hydrogenation of 3‐ylidenephthalides has been developed using the Ir I complex of a spiro[4,4]‐1,6‐nonadiene‐based phosphine‐oxazoline ligand (SpinPHOX) as the catalyst, affording a wide variety of chiral 3‐substituted phthalides in excellent enantiomeric excesses (up to 98 % ee).The utility of the protocol has been … WebAn Ir/SpinPHOX complex catalyzed double asymmetric hydrogenation of 3,6-dialkylidene-1,4-dimethylpiperazine-2,5-dione has been developed, providing an efficient and practical access to a wide ...
WebOct 21, 2003 · The synthesis of the fused aromatic spiroketal core of γ-rubromycin is described via addition of an aryl acetylide fragment to an aryl acetaldehyde fragment. In turn, the aryl acetylene precursor was readily prepared with use of a Sonogashira reaction.
WebThe enantioselective hydrogenation of a series of challenging substrates, α-aryl-β-substituted acrylic acids, was realized with high efficiency and enantioselectivity (up to … free clip art social gatheringsWebOct 1, 2024 · The first asymmetric hydrogenation of 3-ylidenephthalides has been developed using the Ir I complex of a spiro[4,4]-1,6-nonadiene-based phosphine-oxazoline ligand … free clip art sockWebSpinPHOX/Ir catalyst had generality especially toward not only 5~6 membered α-benzylidene ketones but also lactones or lactams (Scheme 10, Equation 1).…” Section : Methods mentioning confidence: 99% free clip art soapWebJul 2, 2024 · One for all: A single SpinPHOX/Ir (SpinPHOX=spiro[4,4]-1,6-nonadiene-based phosphine-oxazoline) catalyst was versatile in asymmetric hydrogenation of several types … blondo tall waterproof bootsWebAug 20, 2024 · An Ir/SpinPHOX complex catalyzed double asymmetric hydrogenation of 3,6-dialkylidene-1,4-dimethylpiperazine-2,5-dione has been developed, providing an efficient … blond peatWeb– Electronic Supplementary Information (ESI) – Highly enantioselective hydrogenation of α-aryl-β-substituted acrylic acids catalyzed by Ir-SpinPHOX Yi Zhang,a,b Zhaobin Han,b Fuying Li,a Kuiling Ding,b,* Ao Zhanga,* a Synthetic Organic & Medicinal Chemistry Laboratory, Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences, 555 … free clip arts of heartsWebIt is confirmed that SpinPHOX/Ir(I) will not be adopting the £20,000-a-year “novelty” strategy. 光学活性的2-羟甲基-3- ... free clipart soldier kneeling at cross